Stem Cells for Neurovascular Repair in Stroke.
Stem Cells for Neurovascular Repair in Stroke.
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干细胞进行中风中的神经血管修复。
DOI：
10.4172/2157-7633.s4-004
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发表时间：
2013-05-01
期刊：
影响因子：
--
通讯作者：
Borlongan CV
中科院分区：
文献类型：
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作者：
Shinozuka K;Dailey T;Tajiri N;Ishikawa H;Kim DW;Pabon M;Acosta S;Kaneko Y;Borlongan CV
Stem cells exert therapeutic effects against ischemic stroke via transplantation of exogenous stem cells or stimulation of endogenous stem cells within the neurogenic niches of subventricular zone and subgranular zone, or recruited from the bone marrow through peripheral circulation. In this paper, we review the different sources of stem cells that have been tested in animal models of stroke. In addition, we discuss specific mechanisms of action, in particular neurovascular repair by endothelial progenitor cells, as key translational research for advancing the clinical applications of stem cells for ischemic stroke.
