Association of Substance Use Disorders with Engagement in Care and Mortality among a Clinical Cohort of People with HIV in Washington, DC.

Association of Substance Use Disorders with Engagement in Care and Mortality among a Clinical Cohort of People with HIV in Washington, DC.
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DOI:
10.1007/s10461-021-03157-4
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发表时间:
2021-07
期刊:
影响因子:
4.4
通讯作者:
DC Cohort Executive Committee
DC Cohort Executive Committee
中科院分区:
医学2区
文献类型:
--
作者:
Doshi RK;Byrne M;Levy M;Varga L;Kuo I;Horberg MA;Castel AD;Monroe AK;DC Cohort Executive Committee

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物质使用障碍(SUDs)在艾滋病毒感染者中很常见,可阻止实现最佳健康结果。利用哥伦比亚特区HIV纵向队列研究(2011-2018)的数据,我们计算了SUD(酒精、兴奋剂和/或阿片类药物使用障碍)的患病率及其相关性,并确定了SUD与参与HIV护理、ART处方、病毒抑制和死亡率的关系。在8420名成年人中,3168名(37.6%)有任何SUD病史,最常见的是酒精使用障碍史(29.6%)。黑人(aOR为1.33)和异性恋者(aOR为1.18)患SUD的风险不成比例,女性患SUD的风险较低(aOR为0.65)。SUD与参与护理、ART处方或病毒抑制无关。SUD与死亡率相关(aHR 1.31)。解决艾滋病毒感染者中的酒精使用障碍和可预防的死亡原因以及药物使用障碍应成为临床护理和公共卫生的优先事项。
Substance use disorders (SUDs) are common among people with HIV and can prevent achievement of optimal health outcomes. Using data from a longitudinal HIV cohort study in the District of Columbia (2011–2018), we calculated the prevalence and correlates of SUD (alcohol, stimulant, and/or opioid use disorders) and determined the association of SUD with engagement in HIV care, ART prescription, viral suppression, and mortality. Of 8420 adults, 3168 (37.6%) had a history of any SUD, most commonly history of alcohol use disorder (29.6%). SUDs disproportionately affected Black individuals (aOR 1.33) and heterosexuals (aOR 1.18), and women had a lower risk of SUD (aOR 0.65). SUD was not associated with engagement in care, ART prescription, or viral suppression. SUD was associated with mortality (aHR 1.31). Addressing alcohol use disorder and preventable causes of death among people with HIV and substance use disorders should be priorities for clinical care and public health.
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