INSULIN-LIKE GROWTH-FACTORS AND CANCER
INSULIN-LIKE GROWTH-FACTORS AND CANCER
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DOI：
10.7326/0003-4819-122-1-199501010-00009
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发表时间：
1995-01-01
影响因子：
39.2
通讯作者：
ROBERTS, CT
中科院分区：
文献类型：
--
作者：
LEROITH, D;BASERGA, R;ROBERTS, CT
胰岛素样生长因子 (IGF) 家族的肽、结合蛋白和受体对于人类正常生长和发育非常重要，并且参与大多数生理系统的特殊功能。 IGF 系统的大多数成员由不同的癌细胞表达，并且可能在这些恶性肿瘤的传播中发挥重要作用。旨在调节 IGF 系统各种成分的新疗法可能会影响癌症的进展和转移。
The insulin-like growth factor (IGF) family of peptides, binding proteins, and receptors are important for normal human growth and development and are involved in the specialized functions of most physiologic systems. Most members of the IGF system are expressed by different cancer cells and may play an important role in the propagation of these malignancies. New therapies aimed at modulating various components of the IGF system could affect the progression and metastasis of cancer.