The influence of aging and sex on skeletal muscle mass and strength
The influence of aging and sex on skeletal muscle mass and strength
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DOI：
10.1097/00075197-200111000-00007
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发表时间：
2001-11-01
影响因子：
3.1
通讯作者：
Doherty, TJ
中科院分区：
文献类型：
--
作者：
Doherty, TJ
这篇简短的综述探讨了衰老对骨骼肌质量和强度的影响，并特别强调了性别相关的差异。众所周知，衰老与肌肉力量的显著下降有关，肌肉力量在生命的第七个十年变得功能重要。肌肉萎缩相关的力量损失主要是继发于男性和女性骨骼肌质量的下降。虽然女性可能比男性经历更早的力量损失，但总体而言，在控制肌肉质量时，与年龄相关的力量下降是相似的。虽然男性可能会经历更大的总肌肉质量损失，但最近的证据表明，老年女性的肌肉质量下降更大。这些差异的影响和潜在的机制进行了讨论。Curr Opin Clin Nutr Metab Care 4：503-508. (C)2001年利平科特威廉姆斯威尔金斯。
This brief review examines the influence of aging on skeletal muscle mass and strength and specifically highlights sex-related differences. It is well established that aging is associated with a significant decline in muscle strength that becomes functionally important by the seventh decade of life. Age-related strength losses are mainly secondary to decline in skeletal muscle mass in men and women. While women may experience earlier strength losses than men, overall, age associated decreases in strength are similar when controlling for muscle mass. Although men may experience greater losses of total muscle mass, recent evidence, however, points toward greater declines in muscle quality in older women. The implications and potential mechanisms for these differences are discussed. Curr Opin Clin Nutr Metab Care 4:503-508. (C) 2001 Lippincott Williams Wilkins.