Transcranial Alternating Current Stimulation (tACS) Enhances Mental Rotation Performance during and after Stimulation.
Transcranial Alternating Current Stimulation (tACS) Enhances Mental Rotation Performance during and after Stimulation.
复制标题
经颅交流电流刺激（TACS）在刺激期间和之后增强了精神旋转性能。
DOI：
10.3389/fnhum.2017.00002
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发表时间：
2017
影响因子：
2.9
通讯作者：
Herrmann CS
中科院分区：
文献类型：
--
作者：
Kasten FH;Herrmann CS
经颅交流电刺激（tACS）已被反复证明以频率特异性方式调节内源性脑振荡。因此，它是一个很有前途的工具，揭示脑振荡和行为或感知之间的因果关系。虽然tACS已被证明会引起长达70分钟的生理后效，但尚不清楚如果受试者执行与刺激频带相互作用的复杂任务，是否仍能引起该效应。此外，还没有研究是否后效是行为相关的。在目前的实验中，参与者进行了谢泼德样的心理旋转任务80分钟。10分钟的基线测量后，参与者接受20分钟的tACS在他们的个人α频率（IAF）或假刺激（30秒tACS在刺激期开始）。然后记录另外50分钟的刺激后EEG。在整个实验过程中，获得任务绩效和脑电。虽然tACS对反应时间或事件相关电位（ERP）没有影响，但结果显示，与假手术组相比，刺激组在刺激期间和刺激后的心理旋转表现有所增加。这伴随着刺激组中持续的α功率和相干性增加以及α频带中的事件相关去极化（ERD）。目前的研究表明，tACS的行为和生理后果并行。这表明在与α波段相互作用的任务期间可能会引起tACS的后遗症。因此，tACS后效适用于实现实验操作。
Transcranial alternating current stimulation (tACS) has been repeatedly demonstrated to modulate endogenous brain oscillations in a frequency specific manner. Thus, it is a promising tool to uncover causal relationships between brain oscillations and behavior or perception. While tACS has been shown to elicit a physiological aftereffect for up to 70 min, it remains unclear whether the effect can still be elicited if subjects perform a complex task interacting with the stimulated frequency band. In addition, it has not yet been investigated whether the aftereffect is behaviorally relevant. In the current experiment, participants performed a Shepard-like mental rotation task for 80 min. After 10 min of baseline measurement, participants received either 20 min of tACS at their individual alpha frequency (IAF) or sham stimulation (30 s tACS in the beginning of the stimulation period). Afterwards another 50 min of post-stimulation EEG were recorded. Task performance and EEG were acquired during the whole experiment. While there were no effects of tACS on reaction times or event-related-potentials (ERPs), results revealed an increase in mental rotation performance in the stimulation group as compared to sham both during and after stimulation. This was accompanied by increased ongoing alpha power and coherence as well as event-related-desynchronization (ERD) in the alpha band in the stimulation group. The current study demonstrates a behavioral and physiological aftereffect of tACS in parallel. This indicates that it is possible to elicit aftereffects of tACS during tasks interacting with the alpha band. Therefore, the tACS aftereffect is suitable to achieve an experimental manipulation.