High specific activity carbon-11 labelling of benzodiazepines: Diazepam and flunitrazepam
High specific activity carbon-11 labelling of benzodiazepines: Diazepam and flunitrazepam
复制标题
苯二氮卓类药物的高比活性碳 11 标记：地西泮和氟硝西泮
DOI：
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发表时间：
1980
期刊：
影响因子：
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通讯作者：
D. Comar
中科院分区：
文献类型：
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作者：
M. Maziére;J. ;G. Berger;C. Prenant;D. Comar
In order to study “in vivo” the brain specific receptor sites of benzodiazepines, a method for carbon-11 labelling of diazepam and flunitrazepam without irradiation risk to personnel is described. 70 mCi (max. 140 mCi) of injectable labelled product, chemically and radiochemically pure, are obtained in 45 minutes with a specific activity of 810 Ci/m mole.
