STATE DEPENDENT ACTIVITY IN MONKEY VISUAL-CORTEX .1. SINGLE CELL-ACTIVITY IN V1 AND V4 ON VISUAL TASKS
STATE DEPENDENT ACTIVITY IN MONKEY VISUAL-CORTEX .1. SINGLE CELL-ACTIVITY IN V1 AND V4 ON VISUAL TASKS
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DOI：
10.1007/bf00247569
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发表时间：
1988-01-01
影响因子：
2
通讯作者：
SCHILLER, PH
中科院分区：
文献类型：
--
作者：
HAENNY, PE;SCHILLER, PH
本研究探讨了在何种程度上的反应的单个细胞在纹状皮层（V1）和纹外皮层（V4）的警觉恒河猴调制的视觉刺激，其相关性的行为任务是不同的。动物必须检测视觉模式的重复（即检测相似性），之前是两种不同模式之间的随机交替次数。将最后一个奖励相关刺激产生的反应与序列中较早的相同刺激产生的反应进行比较。V1的调节作用是中等的：31%的细胞（63/200）显示出对最后一个奖励条件刺激的反应增量为20%或更多。在V4中，效果更加明显：72%的细胞（154个中的110个）显示出超过20%的调节作用。在V4，但不是在V1方向调谐曲线显示了显着收窄，以及一个峰值响应增量的行为显着的刺激，这表明一个功能特定的机制与检测的相似性。虽然在许多细胞中观察到的反应递减过程中的重复交替，这种影响是显着小于调制产生的检测相似性。控制包括介绍新的刺激，在介绍序列，没有产生增强的反应。据推测，有报告的功能特定的影响产生的高阶反馈系统。
This study examined the extent to which the responses of single cells in the striate cortex (V1) and the extrastriate cortex (V4) of the alert rhesus monkey are modulated by visual stimuli whose relevance in a behavioral task is varied. The animal had to detect the repetition of a visual pattern (i.e. detect similarity), preceded by a randomized number of alternations between two different patterns. The responses produced by the last, reward contingent stimulus were compared with responses obtained to that same stimulus earlier in the sequence. Modulatory effects in V1 were moderate: 31% of the cells (63 of 200) showed response increments of 20% or more to the last, reward contingent stimulus. In V4 the effects were much more pronounced: 72% of the cells (110 of 154) showed modulatory effects of more than 20%. in V4 but not in V1 orientation tuning curves showed a significant narrowing as well as a peak response increment to the behaviorally salient stimulus, suggesting a feature specific mechanism associated with the detection of similarity. Although a response decrement was observed in many cells during the repeated alternations, this effect was significantly smaller than the modulation produced by the detection of similarity. Controls included the presentation of novel stimuli during the presentation sequence which did not produce an enhanced response. It is hypothesized that the feature specific effects reported there are produced by higher order feedback systems.