Genomic profiling to promote a healthy lifestyle: not ready for prime time

Genomic profiling to promote a healthy lifestyle: not ready for prime time
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DOI:
10.1038/ng0803-347
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发表时间:
2003-08-01
期刊:
影响因子:
30.8
通讯作者:
Burke, W
Burke, W
中科院分区:
生物学1区
文献类型:
--
作者:
Haga, SB;Khoury, MJ;Burke, W

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基因组分析有可能带来个性化医疗保健和疾病预防的革命。但支持基因组分析的证据并不一致,而且缺乏基于此类测试的健康结果益处的数据。为了使基因组分析变得有效和有用,需要设计良好的流行病学研究和基于基因型的推荐干预措施的彻底临床评估。
Genomic profiling has the potential to usher in a revolution of personalized healthcare and disease prevention. But evidence to support genomic profiling is inconsistent, and data on the health outcome benefits based on such testing are lacking. For genomic profiling to become valid and useful, well designed epidemiologic studies and thorough clinical evaluations of recommended interventions based on genotype are required.