Antibody Response and Disease Severity in Healthcare Worker MERS Survivors.

Antibody Response and Disease Severity in Healthcare Worker MERS Survivors.
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DOI:
10.3201/eid2206.160010
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发表时间:
2016-06
影响因子:
11.8
通讯作者:
Perlman S
Perlman S
中科院分区:
医学2区
文献类型:
--
作者:
Alshukairi AN;Khalid I;Ahmed WA;Dada AM;Bayumi DT;Malic LS;Althawadi S;Ignacio K;Alsalmi HS;Al-Abdely HM;Wali GY;Qushmaq IA;Alraddadi BM;Perlman S

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我们研究了9名医护人员在吉达,沙特阿拉伯,谁幸存的中东呼吸综合征,通过使用系列ELISA和间接免疫荧光试验检测抗体反应。在经历过严重肺炎的患者中,抗体在感染后>18个月才被检测到。抗体寿命在经历过较轻疾病的患者中变化更大。
We studied antibody response in 9 healthcare workers in Jeddah, Saudi Arabia, who survived Middle East respiratory syndrome, by using serial ELISA and indirect immunofluorescence assay testing. Among patients who had experienced severe pneumonia, antibody was detected for >18 months after infection. Antibody longevity was more variable in patients who had experienced milder disease.