Making Cells Worthwhile: Calculations of Value in a European Consortium for Induced Pluripotent Stem Cell Banking
Making Cells Worthwhile: Calculations of Value in a European Consortium for Induced Pluripotent Stem Cell Banking
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DOI：
10.1080/09505431.2018.1538331
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发表时间：
2019-01-02
影响因子：
2.6
通讯作者：
Morrison, Michael
中科院分区：
文献类型：
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作者：
Morrison, Michael
StemBANCC财团是一个大型欧洲财团，汇集了来自学术机构和制药行业的科学家。该联盟的目标是从患有各种常见复杂疾病的参与者中产生1500个诱导多能干细胞（iPSC）系。这些细胞系旨在帮助开发iPSC作为筛选小分子候选药物和体外模拟人类疾病的工具。对这个和其他生物库的投资规模将iPSC视为一种有价值的商品。然而，StemBANCC也被授权在非营利的基础上向欧洲研究人员提供细胞和数据。为了了解如何将这些数量的干细胞和数据配置为财团合作伙伴的有价值和有价值的投资，使用Valuation Studies的理论工具分析了研究材料（项目文件，科学文献和对StemBANCC科学家的采访）。结合STS和经济社会学，评估研究分析了事物，思想和现象的价值如何从特定背景的评估和评价实践中产生;价值包括道德，财务，科学，经济。价值的社会和文化记录。从这个意义上说，从业者评估StemBANCC细胞和数据在各种网站的价值，从参与者招募到在线数据库。这为生物价值和类似的概念模型提供了一种替代方法，用于理论化生命科学中的价值生成。
The StemBANCC consortium was a large European consortium bringing together scientists from academic institutions and the pharmaceutical industry. The aim of the consortium was to produce 1500 induced pluripotent stem cell (iPSC) lines from participants with a variety of common, complex diseases. These cell lines were intended to help develop iPSC as tools for screening small molecule drug candidates and modelling human diseases in vitro. The scale of investment in this and other biobanks presents iPSC as a valuable commodity. However, StemBANCC was also mandated to make its making cells and data available to European researchers on a not-for-profit basis. To understand how making this quantity of stem cells and data available is configured as a valuable and worthwhile investment for the consortium partners, research materials (project documents, scientific literature and interviews with scientists working on StemBANCC) were analysed using theoretical tools from Valuation Studies. Combining STS and economic sociology, valuation studies analyse how the worth of things, ideas and phenomena result from context-specific practices of assessment and evaluation; worth incorporates moral, financial, scientific, economic. social and cultural registers of value. In this sense, practitioners evaluate the worth of the StemBANCC cells and data at a variety of sites, from participant recruitment to online databases. This provides an alternative to biovalue and similar conceptual models for theorising the generation of value in the Life Sciences.