Torque generation by the flagellar rotary motor.

Torque generation by the flagellar rotary motor.
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DOI:
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发表时间:
1995-04
影响因子:
3.4
通讯作者:
H. Berg
H. Berg
中科院分区:
生物学3区
文献类型:
--
作者:
H. Berg

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本文对鞭毛旋转马达的结构和动力学进行了综述。驱动拴系细菌(通过单个鞭毛固定在基质上的细胞)的马达中的力产生元件在以1微米/秒的速度移动时施加20 pN的力。在驱动一束鞭毛丝的马达中,力产生元件施加的力要低10倍,但移动速度要高10倍以上。电机的转矩-速度关系已被测量在一个很宽的动态范围。马达强烈抵抗向后驱动,并且容易损坏。
A review is given of the structure and dynamics of the flagellar rotary motor. Force-generating elements in a motor driving a tethered bacterium (a cell fixed to the substratum by a single flagellum) exert forces of order 20 pN while moving at speeds of order 1 micron/s. Force-generating elements in a motor driving a flagellar filament in a bundle exert forces some 10-fold lower but move at speeds more than 10-fold higher. The motor torque-speed relationship has been measured over a wide dynamic range. Motors strongly resist being driven backwards and are easily broken.