A randomized trial of acupuncture as an adjunctive therapy in osteoarthritis of the knee
A randomized trial of acupuncture as an adjunctive therapy in osteoarthritis of the knee
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DOI：
10.1093/rheumatology/38.4.346
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发表时间：
1999-04-01
期刊：
影响因子：
5.5
通讯作者：
Hochberg, M
中科院分区：
文献类型：
--
作者：
Berman, BM;Singh, BB;Hochberg, M
Objective.本研究的目的是探讨针灸作为标准护理的后续疗法对缓解老年膝关节骨关节炎（OA）患者疼痛和功能障碍的疗效。73例膝关节症状性OA患者随机分配至治疗组（针灸）或标准护理组（对照组）。对结转的末次评分进行分析，以解释在完成前脱落的患者。患者在基线和第4、8和12周时对西安大略和麦克马斯特大学骨关节炎指数（WOMAC）和Lequesne指数进行自我评分。对照组在治疗12周后给予针刺治疗。将这些患者的数据与原始针刺组的数据进行组内分析。与仅接受标准治疗的患者相比，随机接受针灸治疗的患者WOMAC和Lequesne指数均有所改善。在第4周和第8周观察到总WOMAC量表的显著差异。在停止治疗后4周（首次治疗后12周），效果似乎略有下降。结论：针刺治疗慢性前列腺炎无明显不良反应。这些数据表明，针灸是一种有效和安全的常规护理治疗膝关节骨性关节炎患者的后续治疗。
Objective. The purpose of this study was to investigate the efficacy of acupuncture as an adjunctive therapy to standard care for the relief of pain and dysfunction in elderly patients with osteoarthritis (OA) of the knee.Methods. Seventy-three patients with symptomatic OA of the knee were randomly assigned to treatment (acupuncture) or standard care (control). Analysis was performed on last score carried forward to account for patients who dropped out before completion. Patients self-scored Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Lequesne indices at baseline and at 4, 8 and 12 weeks. Patients in the control group were offered acupuncture treatment after 12 weeks. The data for these patients are pooled with those from the original acupuncture group for within-group analysis.Results. Patients randomized to acupuncture improved on both WOMAC and Lequesne indices compared to those who received standard treatment alone. Significant differences on total WOMAC Scale were seen at 4 and 8 weeks. There appears to be a slight decline in effect at 4 weeks after cessation of treatment (12 weeks after first treatment). No adverse effects of acupuncture were reported.Conclusion. These data suggest that acupuncture is an effective and safe adjunctive therapy to conventional care for patients with OA of the knee.