Fun with radicals: Some new perspectives for organic synthesis
Fun with radicals: Some new perspectives for organic synthesis
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DOI：
10.1351/pac-con-10-08-07
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发表时间：
2011-01-01
影响因子：
1.8
通讯作者：
Zard, Samir Z.
中科院分区：
文献类型：
--
作者：
Quiclet-Sire, Beatrice;Zard, Samir Z.
黄原酸酯在烯烃上的退化自由基加成-转移允许快速组装富含功能化的结构。因此可以容易地获得开链、环状和多环化合物的各种家族。此外，通过利用使用过氧化物作为引发剂和化学计量氧化剂的可能性，该方法可以扩展到芳香族和杂芳香族衍生物的合成或改性。本文简要介绍了用RAFT/MADIX（可逆加成-断裂转移/黄原酸酯交换大分子设计）工艺对现有聚合物进行改性和控制合成嵌段聚合物的方法。
The degenerative radical addition-transfer of xanthates onto alkenes allows the rapid assembly of richly functionalized structures. Various families of open-chain, cyclic, and polycyclic compounds can thus be readily accessed. Furthermore, the process can be extended to the synthesis or modification of aromatic and heteroaromatic derivatives by exploiting the possibility of using peroxides both as initiators and stoichiometric oxidants. The modification of existing polymers and the controlled synthesis of block polymers by what is now known as the RAFT/MADIX (reversible addition-fragmentation transfer/macro-molecular design by interchange of xanthate) process is described briefly.