Including genotypic information in genetic evaluations increases the accuracy of sheep breeding values
Including genotypic information in genetic evaluations increases the accuracy of sheep breeding values
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DOI：
10.1111/jbg.12771
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发表时间：
2023-04-01
影响因子：
2.6
通讯作者：
Conington, Joanne
中科院分区：
文献类型：
--
作者：
Kaseja, Karolina;Mucha, Sebastian;Conington, Joanne
纳入全基因组基因型的影响育种值预测英国特克塞尔羊在这篇文章中解决。主要目的是研究当将动物基因型信息纳入遗传评价时EBV准确度值的变化水平。描述了一系列羔羊生长、胴体组成和健康性状的新遗传参数，并将其应用于估计近822，000头动物的常规育种值（EBV）以及添加10，143种基因型后的基因组育种值（gEBV）。主成分分析表明，没有主要的不同群体，因此，人口主要是同质和遗传连锁。结果表明，对于未进行表型分析但与参考群体有良好联系的动物，观察到准确性的最高变化。这尤其见于低遗传性健康性状，从而证明在育种值估计中使用基因型可通过产生更准确的值（尤其是对于年轻的、未表型化的动物）来加速遗传增益。
The impact of inclusion of genome-wide genotypes into breeding value predictions for UK Texel sheep is addressed in this article. The main aim was to investigate the level of change in the accuracy values for EBVs when information from animal genotypes is incorporated into the genetic evaluations. New genetic parameters for a range of lamb growth, carcass composition and health traits are described and applied in the estimation of conventional breeding values (EBVs) for almost 822,000 animals as well as genomic breeding values (gEBVs) after adding 10,143 genotypes. Principal component analyses showed that there are no major distinct groups; hence, the population is mainly homogenous and genetically well-linked. Results suggested that the highest change in accuracy was observed for the animals that are not phenotyped but have good links to the reference population. This was seen especially for the lowly heritable health traits thereby proving that the use of genotypes in breeding values estimation may accelerate the genetic gain by producing more accurate values especially for young, un-phenotyped animals.