Stable lanthanide luminescence agents highly emissive in aqueous solution:: Multidentate 2-hydroxyisophthalamide complexes of SM3+, Eu3+, Tb3+, Dy3+
Stable lanthanide luminescence agents highly emissive in aqueous solution:: Multidentate 2-hydroxyisophthalamide complexes of SM3+, Eu3+, Tb3+, Dy3+
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DOI：
10.1021/ja0379363
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发表时间：
2003-11-05
影响因子：
15
通讯作者：
Raymond, KN
中科院分区：
文献类型：
--
作者：
Petoud, S;Cohen, SM;Raymond, KN
高效的镧系元素 (Ln) 发光探针需要良好的配体-金属能量转移和高水稳定性。报道了基于 2-羟基间苯二甲酰胺螯合单元的配体家族。它们形成高度稳定的八配位 Ln 配合物。其中一些（Ln = Sm、Eu、Tb、Dy）在可见光区域发射，具有良好的配体到镧系元素的能量转移。两种 Tb 配合物研究的绝对量子产率 (Φ = 0.59, 0.61) 和高吸光度使这些成为用于时间分辨检测的最亮的发光探针；一种配合物的发射光谱可以低至10-15M。四种不同 Ln 复合物的低重叠使其能够同时检测和区分。
Efficient lanthanide (Ln) luminescent probes require good ligand-to-metal energy transfer and high aqueous stability. A family of ligands based on 2-hydroxyisophthalamide chelating units is reported. These form highly stable, eight-coordinate Ln complexes. Several of these (Ln = Sm, Eu, Tb, Dy) emit in the visible region with good ligand-to-lanthanide energy transfer. The absolute quantum yields of the two Tb complexes studies (Φ = 0.59, 0.61) and high absorbance make these the brightest luminescent probes for time-resolved detection; the emission spectrum of one complex can be seen down to 10-15M. The low overlap of the four different Ln complexes enables their simultaneous detection and discrimination.