Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)

Amiloride derived inhibitors of acid-sensing ion channel-3 (ASIC3)
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DOI:
10.1016/j.bmcl.2009.03.029
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发表时间:
2009-05-01
影响因子:
2.7
通讯作者:
Bock, Mark G.
Bock, Mark G.
中科院分区:
医学4区
文献类型:
--
作者:
Kuduk, Scott D.;Di Marco, Christina N.;Bock, Mark G.

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A series of amiloride derivatives modified at the 5-position of the pyrazine ring were evaluated as inhibitors of acid-sensing ion channel-3 (ASIC3), a novel target for the treatment of chronic pain. (C) 2009 Elsevier Ltd. All rights reserved.