Enantioselective Aza-MichaelAddition to Conjugated Nitroenynes Catalyzed by Chiral ArylaminophosphoniumBarfates
Enantioselective Aza-MichaelAddition to Conjugated Nitroenynes Catalyzed by Chiral ArylaminophosphoniumBarfates
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DOI：
10.1055/s-0030-1260541
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发表时间：
2011-06
期刊：
影响因子：
2
通讯作者：
D. Uraguchi;N. Kinoshita;Tomohito Kizu;T. Ooi
中科院分区：
文献类型：
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作者：
D. Uraguchi;N. Kinoshita;Tomohito Kizu;T. Ooi
本文研究了共轭氮炔的不对称氮杂迈克尔加成反应。β-螺环杂手性芳氨基膦巴氏盐1b·BArF有效地催化了该反应，得到了相应的共轭加合物β-氨基高炔丙基硝基化合物，化学产率高，对映选择性高.
Enantioselective aza-Michael addition to conjugated nitroenynes has been developed. P-Spiro heterochiral arylaminophosphonium barfate 1b·BArF effectively catalyzes the reaction, and the corresponding conjugate adducts, β-amino homopropargylic nitro compounds, are obtained in good chemical yields with high enantioselectivities.