Conscious recollection and the human hippocampal formation: Evidence from positron emission tomography
Conscious recollection and the human hippocampal formation: Evidence from positron emission tomography
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DOI：
10.1073/pnas.93.1.321
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发表时间：
1996-01-09
影响因子：
11.1
通讯作者：
Albert, MS
中科院分区：
文献类型：
--
作者：
Schacter, DL;Alpert, NM;Albert, MS
我们使用正电子发射断层扫描(PET)来研究海马区结构在内隐和外显记忆中的作用。人类志愿者研究了一系列熟悉的单词，然后他们要么提供脑海中第一个出现在三个字母提示下的单词(内隐记忆)，要么尝试回忆相同线索下的被学习单词(外显记忆)，没有证据表明海马区的激活与内隐记忆有关，然而，内隐记忆测试的启动效应与纹外视皮层的活动减少有关。在外显记忆测试中，受试者在一个条件下回忆了许多目标单词，在第二个条件下回忆了很少的单词，尽管他们试图记住它们。两种情况的比较表明，海马区血流量的增加与有意识地回忆学习的单词有关，而额区的血流量增加与提取目标词的努力有关，我们的结果有助于澄清关于海马区在人类记忆中的作用的一些谜题。
We used positron emission tomography (PET) to examine the role of the hippocampal formation in implicit and explicit memory. Human volunteers studied a list of familiar words, and then they either provided the first word that came to mind in response to three-letter cues (implicit memory) or tried to recall studied words in response to the same cues (explicit memory), There was no evidence of hippocampal activation in association with implicit memory, However, priming effects on the implicit memory test were associated with decreased activity in extrastriate visual cortex, On the explicit memory test, subjects recalled many target words in one condition and recalled few words in a second condition, despite trying to remember them. Comparisons between the two conditions showed that blood-flow increases in the hippocampal formation are specifically associated with the conscious recollection of studied words, whereas bloodflow increases in frontal regions are associated with efforts to retrieve target words, Our results help to clarify some puzzles concerning the role of the hippocampal formation in human memory.