Zika Virus Vaccines: Challenges and Perspectives.
Zika Virus Vaccines: Challenges and Perspectives.
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DOI:
10.3390/vaccines6030062
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发表时间:
2018-09-13
期刊:
影响因子:
7.8
通讯作者:
Kobinger GP
中科院分区:
文献类型:
--
作者:
das Neves Almeida R;Racine T;Magalhães KG;Kobinger GP
Zika virus is an arbovirus that has rapidly spread within the Americas since 2014, presenting a variety of clinical manifestations and neurological complications resulting in congenital malformation, microcephaly, and possibly, in male infertility. These significant clinical manifestations have led investigators to develop several candidate vaccines specific to Zika virus. In this review we describe relevant targets for the development of vaccines specific for Zika virus, the development status of various vaccine candidates and their different platforms, as well as their clinical progression.
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