METOPROLOL COMPARED WITH PROPRANOLOL IN THE TREATMENT OF ESSENTIAL TREMOR
METOPROLOL COMPARED WITH PROPRANOLOL IN THE TREATMENT OF ESSENTIAL TREMOR
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DOI：
10.1001/archneur.1984.04050140069026
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发表时间：
1984-01-01
影响因子：
--
通讯作者：
BIARY, N
中科院分区：
文献类型：
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作者：
KOLLER, WC;BIARY, N
本文分析了酒石酸美托洛尔和盐酸普萘洛尔治疗原发性震颤23例的疗效。通过患者自我评估、临床评分和震颤图评估震颤。20例患者中有10例震颤减少与普萘洛尔。23例患者中，美托洛尔减少了13例震颤，包括3例普萘洛尔引起呼吸窘迫的哮喘患者。不良反应不常见。个别患者要么对普萘洛尔和美托洛尔都有反应，要么对两种药物都没有反应。患者年龄、震颤持续时间、震颤频率、家族史或对静脉注射乙醇的反应不能区分反应者和无反应者。
The effects of metoprolol tartrate and propranolol hydrochloride on 23 patients with essential tremor were analyzed. Tremor was assessed by patient self-evaluation, clinical scoring and tremorgrams. Ten of 20 patients had tremor reduction with propranolol. Metoprolol decreased tremor in 13 of 23 patients, including 3 patients with asthma in whom propranolol had caused respiratory distress. Adverse reactions were infrequent. Individual patients either responded to both propranolol and metoprolol or to neither drug. Patient age, duration of tremor, tremor frequency, family history, or response to i.v. ethyl alcohol did not distinguish responders from nonresponders.