Avocado (Persea americana) Seed as a Source of Bioactive Phytochemicals

Avocado (Persea americana) Seed as a Source of Bioactive Phytochemicals
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DOI:
10.2174/1381612811319340007
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发表时间:
2013-10-01
影响因子:
3.1
通讯作者:
Lambert, Joshua D.
Lambert, Joshua D.
中科院分区:
医学4区
文献类型:
--
作者:
Dabas, Deepti;Shegog, Rachel M.;Lambert, Joshua D.

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据报道,鳄梨(Persea americana,Lauraceae)的果肉具有有益心血管健康的作用。鳄梨油用于皮肤病学应用,据报道其不皂化部分对骨关节炎具有有益作用。虽然种子占水果总量的相当大的比例,但对鳄梨种子的植物化学和生物学效应的科学研究仍处于起步阶段。目前,种子是一种未充分利用的资源,也是鳄梨加工商的浪费问题。有关于使用种子治疗与健康有关的疾病的民族药理学信息,特别是在鳄梨流行且目前大规模种植的南美国家。目前的研究表明,鳄梨种子可以改善高胆固醇血症,并可用于治疗高血压,炎症和糖尿病。种子还被发现具有杀虫、杀真菌和抗微生物活性。鳄梨种子和丰富的酚类化合物,这些可能在推定的健康效应中发挥作用。从历史上看,鳄梨种子提取物也被用作书写墨水,我们实验室的研究探索了多酚氧化酶产生的有色鳄梨种子提取物的潜在着色剂特性。在这里,我们回顾了鳄梨种子的生物活性和其他功能特性的现有数据。我们讨论了现有数据的强度,推定的活性化合物,以及未来研究的潜在方向。
The pulp of avocado (Persea americana, Lauraceae) has been reported to have beneficial cardiovascular health effects. Avocado oil is used for dermatological applications and its unsaponifiable portion is reported to have beneficial effects against osteoarthritis. Although the seed represents a considerable percentage of the total fruit, scientific research on the phytochemistry and biological effects of avocado seeds is in the nascent stages,. Currently, the seed represents an under-utilized resource and a waste issue for avocado processors. There is ethno-pharmacological information on the use of seeds for the treatment of health-related conditions, especially in South American countries where avocados are endemic and currently grown on a large scale. Current research has shown that avocado seeds may improve hypercholesterolemia, and be useful in the treatment of hypertension, inflammatory conditions and diabetes. Seeds have also been found to possess insecticidal, fungicidal, and anti-microbial activities. The avocado seeds and rich in phenolic compounds, and these may play a role in the putative health effects. Historically, extracts of avocado seeds were also used as ink for writing and research in our laboratory has explored the potential colorant properties of a polyphenol oxidase-produced colored avocado seed extract. Here, we review the currently-available data on the bioactivity and other functional properties of avocado seeds. We discuss the strength of the available data, the putative active compounds, and potential directions for future studies.