Estrous behavior, luteinizing hormone and estradiol profiles of intact ewes treated with insulin or endotoxin
Estrous behavior, luteinizing hormone and estradiol profiles of intact ewes treated with insulin or endotoxin
复制标题
DOI：
10.1016/j.physbeh.2011.09.025
复制
发表时间：
2012-02-01
影响因子：
2.9
通讯作者：
Dobson, H.
中科院分区：
文献类型：
--
作者：
Fergani, C.;Saifullizam, A. K.;Dobson, H.
急性胰岛素给药导致卵巢完整母羊的发情行为和LH激增之间的差异。为了检查反应的显著变化，在本研究中，我们使用了大量动物来证实胰岛素的发现，并检查内毒素是否具有相同的作用。在繁殖季节期间，完整母羊的卵泡期与孕酮阴道子宫托同步，并在孕酮停药后28小时（时间零点）接受盐水溶媒（n=22;对照）、胰岛素（4 IU/kg; n=21只母羊）或内毒素（LPS; 100 ng/kg; n=10）。在对照组中，LH峰出现在36.5 +/- 5.7 h，首次被公羊安装在38.2 +/- 1.8 h，但延迟了17.6 h（P
Acute insulin administration causes a disparity between the onset of estrous behavior and the LH surge in ovary-intact ewes. To examine the considerable variation in responses, in the present study we used a large number of animals to confirm findings with insulin, and examine whether endotoxin has the same effect. During the breeding season, follicular phases of intact ewes were synchronized with progesterone vaginal pessaries and received saline vehicle (n=22; controls), insulin (4 IU/kg; n=21 ewes) or endotoxin (LPS; 100 ng/kg; n=10) at 28 h after progesterone withdrawal (time zero). In controls, the LH surge onset occurred at 36.5 +/- 5.7 h and were first mounted by a ram at 38.2 +/- 1.8 h, but there was a delay of 17.6 h (P