Extraction of dielectric properties of multiple populations from dielectrophoretic collection spectrum data
Extraction of dielectric properties of multiple populations from dielectrophoretic collection spectrum data
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DOI：
10.1088/0031-9155/50/10/006
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发表时间：
2005-05-21
影响因子：
3.5
通讯作者：
Hughes, MP
中科院分区：
文献类型：
--
作者：
Broche, LM;Labeed, FH;Hughes, MP
在本文中，我们将展示如何简化的假设可以用来提取有用的数据，特别是从介电泳收集光谱的细胞质，从而确定多个群体的细胞内的样品的属性。具体地，观察介电分散的开始频率允许根据细胞质电导率识别和计数细胞群体，特别是与确定用于高通量筛选应用的药物的作用相关。
In this paper we show how simplifying assumptions can be used to extract useful data from the dielectrophoretic collection spectrum, in particular for the cytoplasm, and hence determine the properties of multiple populations of cells within a sample. Specifically, the observation of the frequencies of onset of dielectric dispersion allows the identification and enumeration of populations of cells according to cytoplasmic conductivity, with particular relevance to the determination of the action of drugs for high-throughput screening applications.