BRing it on: new insights into the mechanism of brassinosteroid action
BRing it on: new insights into the mechanism of brassinosteroid action
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DOI：
10.1093/jxb/erh024
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发表时间：
2004-01-01
影响因子：
6.9
通讯作者：
Chory, J
中科院分区：
文献类型：
--
作者：
Nemhauser, JL;Chory, J
最近的几项突破填补了油菜素类固醇（BR）反应的关键细节。BAK1，一种BRI1相互作用蛋白，负调节因子BIN2，以及BIN2，BZR 1和BES 1的直接靶点的鉴定，提供了细胞表面BR感知与细胞核中基因表达调节之间的联系。全局表达研究进一步定义了该途径中的下游事件，证实了在BR水平的负反馈调节中起作用的几个因子的作用。与植物激素生长素的新联系也被发现。
Several recent breakthroughs have filled in key details of the brassinosteroid (BR) response. Identification of BAK1, a BRI1 interacting protein, the negative regulator BIN2, as well as direct targets of BIN2, BZR1 and BES1, provide a link between BR perception at the cell surface and regulation of gene expression in the nucleus. Global expression studies further defined the downstream events in this pathway, confirming the role of several factors acting in negative feedback regulation on BR levels. New links to the plant hormone, auxin, were also uncovered.