Assessing computational tools for the discovery of transcription factor binding sites

Assessing computational tools for the discovery of transcription factor binding sites
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DOI:
10.1038/nbt1053
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发表时间:
2005-01-01
影响因子:
46.9
通讯作者:
Zhu, Z
Zhu, Z
中科院分区:
工程技术1区
文献类型:
--
作者:
Tompa, M;Li, N;Zhu, Z

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调控元件的预测是一个计算方法带来很大希望的问题。在过去几年中,有许多用于此任务的工具可供使用。当前评估有两个目的:就各种情况下现有工具的准确性为用户提供一些指导,以及为评估未来的工具提供数据集的基准。
The prediction of regulatory elements is a problem where computational methods offer great hope. Over the past few years, numerous tools have become available for this task. The purpose of the current assessment is twofold: to provide some guidance to users regarding the accuracy of currently available tools in various settings, and to provide a benchmark of data sets for assessing future tools.