Genomic Analyses and the Origin of the Eukaryotes

Genomic Analyses and the Origin of the Eukaryotes
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DOI:
10.1002/cbdv.200790215
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发表时间:
2007-11
影响因子:
2.9
通讯作者:
M. Rivera
M. Rivera
中科院分区:
化学3区
文献类型:
--
作者:
M. Rivera

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The availability of whole‐genome data has created the extraordinary opportunity to reconstruct in fine details the ‘tree of life’. The application of such comprehensive effort promises to unravel the enigmatic evolutionary relationships between prokaryotes and eukaryotes. Traditionally, biologists have represented the evolutionary relationships of all organisms by a bifurcating phylogenetic tree. But recent analyses of completely sequenced genomes using conditioned reconstruction (CR), a newly developed gene‐content algorithm, suggest that a cycle graph or ‘ring’ rather than a ‘tree’ is a better representation of the evolutionary relationships between prokaryotes and eukaryotes. CR is the first phylogenetic‐reconstruction method to provide precise evidence about the origin of the eukaryotes. This review summarizes how the CR analyses of complete genomes provide evidence for a fusion origin of the eukaryotes.