Recent advances on viral manipulation of NF-κB signaling pathway.
Recent advances on viral manipulation of NF-κB signaling pathway.
复制标题
NF-κB信号通路病毒操纵的最新进展。
DOI：
10.1016/j.coviro.2015.08.013
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发表时间：
2015-12
影响因子：
5.9
通讯作者：
Feng P
中科院分区：
文献类型：
--
作者：
Zhao J;He S;Minassian A;Li J;Feng P
NF-κB transcription factors regulate the expression of hundreds of genes primarily involved in immune responses. Signaling events leading to NF-κB activation constitute a major antiviral immune pathway. To replicate and persist within their hosts, viruses have evolved diverse strategies to evade and exploit cellular NF-κB immune signaling cascades for their benefit. We summarize recent studies concerning viral manipulation of the NF-κB signaling pathway downstream of pattern recognition receptors. Signal transduction mediated by pattern recognition receptors is a research frontier for both infectious disease and innate immunology.
