The prognosis with postherpetic neuralgia
The prognosis with postherpetic neuralgia
复制标题
带状疱疹后神经痛的预后
DOI：
10.1016/0304-3959(91)90076-a
复制
发表时间：
1991
期刊：
影响因子：
7.4
通讯作者：
R. Evans
中科院分区：
文献类型：
--
作者：
C Peter N Watson;V. R. Watt;M. Chipman;N. Birkett;R. Evans
对156例中、重度带状疱疹后遗神经痛患者进行了长达11年的随访。近一半的患者在最终评估(中位数2年)时表现良好，其中超过一半的患者目前没有接受治疗。与良好结果相关的最常用的药物是抗抑郁药、外用辣椒素和各种止痛药。病程越长的PHN预后越差。这些患者中更多的人在随访时使用了某种形式的治疗。一组患者似乎遵循着一个渐进的过程，对本研究中使用的所有治疗都无效。
: One hundred and fifty-six patients with moderate to severe postherpetic neuralgia (PHN) were followed for up to 11 years. Nearly half of all patients were doing well at the final assessment (median 2 years) and more than half of these were on no therapy at this time. The most commonly used agents associated with a good outcome were antidepressants, topical capsaicin and analgesics of various kinds. Longer duration PHN appeared to have a worse prognosis. More of these patients were noted to be using some form of treatment at follow up. A group of patients seemed to follow a progressive course and were refractory to all treatments used in this study.