Advances in adult asthma diagnosis and treatment in 2013
Advances in adult asthma diagnosis and treatment in 2013
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DOI：
10.1016/j.jaci.2013.11.005
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发表时间：
2014-01-01
影响因子：
14.2
通讯作者：
Apter, Andrea J.
中科院分区：
文献类型：
--
作者：
Apter, Andrea J.
2013年出现了几个主题：(1)专门寻找使用新机制的新疗法；(2)免疫系统可塑性的重要性（例如，在一种情况下介导炎症的分子可以促进其消退并在其他情况下恢复体内平衡）；(3)病毒在哮喘加重中的复杂作用；(4)哮喘、吸烟者哮喘与慢性阻塞性肺疾病的异同；(5)了解哮喘表型及其随时间稳定性的重要性。一旦新的治疗方法通过了最初的临床试验，就需要以患者为导向和现实世界的研究。
In 2013, several themes emerged: (1) a dedicated search for new therapies using new mechanisms; (2) the importance of the plasticity of the immune system (eg, that molecules that mediate inflammation in one setting can promote its resolution and return to homeostasis in other circumstances); (3) the complex role of viruses in asthma exacerbations; (4) the similarities and differences among asthma, asthma in smokers, and chronic obstructive pulmonary disease; and (5) the importance of understanding asthma phenotypes and their stability over time. Once new therapeutics pass the initial clinical trials, patient-oriented and real-world research will be needed.