Role of skeletal muscle glucocorticoid receptor in systemic energy homeostasis
Role of skeletal muscle glucocorticoid receptor in systemic energy homeostasis
复制标题
骨骼肌糖皮质激素受体在全身能量稳态中的作用
DOI：
10.1016/j.yexcr.2017.03.049
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发表时间：
2017
影响因子：
3.7
通讯作者：
Yoshikawa Noritada
中科院分区：
文献类型：
--
作者：
Tanaka Hirotoshi;Shimizu Noriaki;Yoshikawa Noritada
糖皮质激素（GC）几乎影响身体的每个器官和组织，调节包括能量稳态在内的各种生理过程。GC的代谢使命是将足够的葡萄糖供应到循环中，以给大脑提供燃料，并确保生物体在急性应激或饥饿条件下的存活。最近的研究表明，GC通过多个器官之间的协调，生理上引起全身能量代谢的微调。
Glucocorticoids (GCs) affect nearly every organ and tissue in the body, regulating diverse physiologic processes including energy homeostasis. The metabolic mission of GCs is to supply enough glucose into the circulation to fuel the brain and ensure survival of the organism under conditions of acute stress or starvation. Recent studies have revealed that GCs, via orchestration between multiple organs, physiologically elicit fine tuning of systemic energy metabolism.