Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary Supplements
Progress in developing analytical and label-based dietary supplement databases at the NIH Office of Dietary Supplements
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DOI：
10.1016/j.jfca.2007.07.010
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发表时间：
2008-02-01
影响因子：
4.3
通讯作者：
Perry, Charles R.
中科院分区：
文献类型：
--
作者：
Dwyer, Johanna T.;Picciano, Mary Frances;Perry, Charles R.
虽然在美国估计有50%的成年人食用膳食补充剂，但经分析证实的关于其生物活性成分的数据很少。由美国国立卫生研究院膳食补充剂办公室（ODS）资助的几个项目加强了膳食补充剂数据库的开发，并有助于更好地描述膳食补充剂对总膳食摄入量的定量和定性贡献。ODS与美国农业部合作，正在开发一个经化学分析核实的膳食补充剂成分数据库。最初选择用于分析验证的产品是成人复合维生素矿物质补充剂（MVMs）。这些产品被广泛使用，分析方法可用于确定关键成分，并且认证的参考物质正在开发中。此外，mvm没有标准的科学、法规或市场定义，并且具有广泛不同的成分、特性和生物利用度。此外，产品中维生素和矿物质的实际含量偏离标签值的程度尚不清楚。最终，DSID将证明对专业人员有用，可以更准确地估计膳食补充剂对总膳食营养素摄入量的贡献，并更好地评估膳食补充剂在促进健康和福祉方面的作用。ODS还与国家卫生统计中心合作，加强国家健康和营养检查调查膳食补充剂标签数据库。最新的ODS努力探索开发在美国销售的所有膳食补充剂标签数据库的可行性和实用性。本文描述了这些项目和支持项目。Elsevier Inc.出版。
Although an estimated 50% of adults in the United States consume dietary supplements, analytically substantiated data on their bioactive constituents are sparse. Several programs funded by the Office of Dietary Supplements (ODS) at the National Institutes of Health enhance dietary supplement database development and help to better describe the quantitative and qualitative contributions of dietary supplements to total dietary intakes. ODS, in collaboration with the United States Department of Agriculture, is developing a Dietary Supplement Ingredient Database (DSID) verified by chemical analysis. The products chosen initially for analytical verification are adult multivitamin-mineral supplements (MVMs). These products are widely used, analytical methods are available for determining key constituents, and a certified reference material is in development. Also MVMs have no standard scientific, regulatory, or marketplace definitions and have widely varying compositions, characteristics, and bioavailability. Furthermore, the extent to which actual amounts of vitamins and minerals in a product deviate from label values is not known. Ultimately, DSID will prove useful to professionals in permitting more accurate estimation of the contribution of dietary supplements to total dietary intakes of nutrients and better evaluation of the role of dietary supplements in promoting health and well-being. ODS is also collaborating with the National Center for Health Statistics to enhance the National Health and Nutrition Examination Survey dietary supplement label database. The newest ODS effort explores the feasibility and practicality of developing a database of all dietary supplement labels marketed in the US. This article describes these and supporting projects. Published by Elsevier Inc.