PathBuilder-open source software for annotating and developing pathway resources
PathBuilder-open source software for annotating and developing pathway resources
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DOI：
10.1093/bioinformatics/btp453
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发表时间：
2009-11-01
期刊：
影响因子：
5.8
通讯作者：
Pandey, Akhilesh
中科院分区：
文献类型：
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作者：
Kandasamy, Kumaran;Keerthikumar, Shivakumar;Pandey, Akhilesh
我们已经开发了Path Builder，这是一个开源的Web应用程序，用于注释与信号通路有关的生物信息，并创建基于Web的途径资源。PathBuilder能够手动或通过自动从其他数据库导入数据来注释分子事件，包括蛋白质-蛋白质相互作用、酶-底物关系和蛋白质转位事件。PathBuilder的显著功能包括数据格式的自动验证、用于路径可视化的内置模块、从其他路径资源自动导入数据、以几种标准数据交换格式导出数据以及用于检索现有路径数据集的应用编程接口。
We have developed PathBuilder, an open-source web application to annotate biological information pertaining to signaling pathways and to create web-based pathway resources. PathBuilder enables annotation of molecular events including protein-protein interactions, enzyme-substrate relationships and protein translocation events either manually or through automated importing of data from other databases. Salient features of PathBuilder include automatic validation of data formats, built-in modules for visualization of pathways, automated import of data from other pathway resources, export of data in several standard data exchange formats and an application programming interface for retrieving existing pathway datasets.