The distribution of gene frequencies under irreversible mutation
The distribution of gene frequencies under irreversible mutation
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DOI：
10.1073/pnas.24.7.253
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发表时间：
1938-01-01
影响因子：
11.1
通讯作者：
Wright, S
中科院分区：
文献类型：
--
作者：
Wright, S
本文给出了不可逆突变基因频率分布在形式平衡下必须成立的方程组。分布本身的公式是在各种情况下推导出来的，包括突变是可逆的，或者如果是不可逆的，则受到强选择的反对;没有选择，但有任何数量级的相反突变率;以及人口如此之小，突变压力对分布形式没有影响。的进化意义的结果进行了简要讨论。
This paper de-velops equations which must hold under equilibrium of form in the distribution of frequencies of a gene subject to irreversible mutation. The formula of the distribution itself is derived for various cases, including the case in which mutation is reversible or, if irreversible, is opposed by strong selection, that in which there is no selection but opposed mutation rates of any magnitudes, and that in which the population is so small that mutation pressures have no effect on the form of distribution. The evolutionary significance of the results is discussed briefly.