Preabsorptive factors are not the main determinants of intake depression induced by a high-protein diet in the rat
Preabsorptive factors are not the main determinants of intake depression induced by a high-protein diet in the rat
复制标题
前吸收因素不是高蛋白饮食引起大鼠摄入抑制的主要决定因素
DOI：
10.1016/j.physbeh.2004.02.029
复制
发表时间：
2004
影响因子：
2.9
通讯作者：
G. Fromentin
中科院分区：
文献类型：
--
作者：
D. L’Heureux;D. Tomé;A. Bensaid;C. Morens;Magali Lacroix;J. Huneau;G. Fromentin
高蛋白饮食导致食物摄入量减少的相关因素仍然知之甚少。本研究的目的是评估几个preingestive或preabsorption因素可能会影响食物的摄入量时，大鼠随意喂养的作用。在改变高蛋白饮食的组成后测量食物摄入，即，蛋白质或碳水化合物的类型。此外，还研究了高蛋白饮食摄入量与液体摄入量或胃体积之间的相关性。通过改变高蛋白饮食的碳水化合物组成（蔗糖/玉米淀粉）和蛋白质来源（大豆或面筋或总乳蛋白），我们修改了这些饮食的orosensory属性。然而，在过渡阶段或适应后，这些大鼠组之间的食物摄入量没有差异，除了在第一天的大豆或麸质为基础的饮食时，抑郁症的食物摄入量加剧。高蛋白饮食摄入量的下降既不是由于吃高蛋白饮食引起的增加液体摄入量所需的任何延迟的结果，也不是由于胃体积的显着增加，这可能解释了通过激活迷走传入纤维增强饱腹感和减少食物摄入量。我们的实验并没有表明口咽或前吸收因子在高蛋白饮食引起的食物摄入抑制中的优势作用。
The factors involved in the depression of food intake produced by a high-protein diet are still poorly understood. The aim of this study was to assess the role of several preingestive or preabsorptive factors likely to influence food intake when rats were fed ad libitum. Food intake was measured after modifying the composition of the high-protein diet, i.e., the type of proteins, or carbohydrates. Moreover, correlations between high-protein diet intake and the quantity of fluid ingested or stomach volume were studied. By varying the carbohydrate composition (sucrose/cornstarch) and the protein source (soy or gluten or total milk protein) of high-protein diets, we modified the orosensory properties of these diets. However, no differences in food intake were observed between these groups of rats during the transition phase or after adaptation, except during the first day of soy- or gluten-based diets when the depression of food intake was intensified. The depression of high-protein diet intake was neither the consequence of any delay necessary to increase the fluid intake induced by eating a high-protein diet nor due to a marked increase in stomach volume, which might explain enhanced satiety and decreased food intake through the activation of vagal afferent fibers. Our experiments do not indicate a preponderant role for oropharyngeal or preabsorptive factors in the depression of food intake induced by a high-protein diet.
DOI：
10.1093/jn/119.5.677
发表时间：
1989-05
期刊：
The Journal of nutrition
影响因子：
--
作者：
A. E. Harper;John C. Peters
通讯作者：
A. E. Harper;John C. Peters
膳食蛋白质对食物摄入、组织氨基酸和大脑血清素的急性影响。
DOI：
10.1152/ajpregu.1987.252.5.r902
发表时间：
1987
期刊：
The American journal of physiology
影响因子：
--
作者：
Peters,JC;Harper,AE
通讯作者：
Harper,AE
影响因子：
4.2
作者：
PETERS, JC;HARPER, AE
通讯作者：
HARPER, AE