Iron and Parenteral Nutrition
Iron and Parenteral Nutrition
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DOI：
10.1053/j.gastro.2009.08.013
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发表时间：
2009-11-01
期刊：
影响因子：
29.4
通讯作者：
Forbes, Alastair
中科院分区：
文献类型：
--
作者：
Forbes, Alastair
有充分的证据表明铁是一种必需的微量元素，但对接受肠外营养（PN）的患者的铁状态的评估以及所需量和输送方式的决定尚不清楚。尽管在急性疾病期间铁的需求量可能会减少，但失血和铁缺乏的频繁同时发生强烈主张维持与基础需求一致的分娩水平。维持铁的供应被认为不太可能存在风险，但新的数据对此提出了质疑。哺乳期、怀孕期和哺乳期妇女的需求比成年男子的需求更大。证据支持成年男性和绝经后女性每天静脉注射约1 mg元素铁。可以支持妊娠期妇女1.5 g/d和妊娠后期或哺乳期妇女2.0 g/d的剂量。成长中的孩子需要一个校准的反应。建议继续监测铁的状态。铁是大多数PN方案的重要组成部分。所含铁的数量应考虑到预计的需求。
There is ample evidence that iron is an essential trace element, but assessment of iron status and decisions on the amounts needed and the means of delivery in patients on parenteral nutrition (PN) have been unclear. Although iron requirements may diminish during acute illness, the frequent concurrence of blood loss and iron deficiency argue strongly for maintenance of levels of delivery in line with basal requirements. Maintenance of iron delivery has not been thought likely to present risk, but new data are questioning this. The needs of menstruating, pregnant, and lactating women are greater than those of adult men. The evidence favors an intravenous dose of around 1 mg of elemental iron per day in adult men and postmenopausal women. Doses of 1.5 g/d in menstruating women and 2.0 g/d for those in the later stages of pregnancy or lactating can be supported. A calibrated response is required in the growing child. Continued monitoring of iron status is recommended. Iron is an essential component for most PN regimens. The quantity of iron to be included should take account of predicted requirements.