AN EXPERIMENTAL-STUDY OF THE CHANGES IN PIGMENTATION IN HUMAN-SKIN INVIVO WITH VISIBLE AND NEAR-INFRARED LIGHT
AN EXPERIMENTAL-STUDY OF THE CHANGES IN PIGMENTATION IN HUMAN-SKIN INVIVO WITH VISIBLE AND NEAR-INFRARED LIGHT
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DOI：
10.1111/j.1751-1097.1984.tb03905.x
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发表时间：
1984-01-01
影响因子：
3.3
通讯作者：
BAQER, A
中科院分区：
文献类型：
--
作者：
KOLLIAS, N;BAQER, A
使用390-1700 nm光源，通过光纤束照射志愿者下臂内侧的皮肤，照射次数高达1.2倍。 104 秒，功率高达 0.35 W/cm2。在照射的同时，测量反射强度的光谱(390-720nm)，同时将纤维束周围直径5.0cm的皮肤区域保持在恒定温度，误差在0.2℃以内。 C. 观察并测量光产物的产生，并测量照射开始后 600 秒（10 分钟）内发射强度的变化。形成的光产物的特征是在光谱的蓝色部分（400-450 nm）有弱吸收，导致仅在照射区域出现蓝色外观。颜色变化表现为一个两步过程。它以可溶性光产物开始，其在照射后24小时内消失，并且不溶性光产物在照射大于3次时出现。 103 秒（50 分钟）。两种光产物之间没有检测到光谱差异。不溶性光产物的持续时间长达 8 周。皮肤的颜色变化是立即的，并且没有与这种颜色变化相关的红斑。
The skin of the lower inner arm of volunteers was irradiated, with a 390-1700 nm light source, through a fiber optic bundle for times of up to 1.2 .times. 104 s and with powers of up to 0.35 W/cm2. Simultaneously with the irradiation, spectra (390-720 nm) of the remitted intensity were measured, while a 5.0 cm in diameter area of the skin around the fiber bundle was maintained at constant temperature, within 0.2.degree. C. The generation of a photoproduct was observed and measured as changes in the remitted intensity within 600 s (10 min) of the start of irradiation. The photoproduct formed was characterized by a weak absorption in the blue part of the spectrum (400-450 nm), leading to a bluish appearance in the irradiated area only. The color change appears as a 2 step process. It starts with a soluble photoproduct, which disappears, within 24 h after irradiation, and an insoluble photoproduct which appears with irradiation greater than 3 .times. 103 s (50 min). No spectral differences were detected between the 2 photoproducts. The insoluble photoproduct persists for periods of up to 8 wk. The color change in the skin is immediate and there is no erythema associated with this color change.