Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells.
Mitochondria-targeted fluorescent polymersomes for drug delivery to cancer cells.
复制标题
用于向癌细胞递送药物的线粒体靶向荧光聚合物囊泡。
DOI：
10.1039/c6py00623j
复制
发表时间：
2016
影响因子：
4.6
通讯作者：
Mallik,S
中科院分区：
文献类型：
--
作者：
Kulkarni,PS;Haldar,MK;Confeld,MI;Langaas,CJ;Yang,X;Qian,SY;Mallik,S
线粒体是一个有吸引力的靶点，以提供抗癌药物。我们已经合成了一种阳离子三苯基膦离子共轭荧光聚合物，自组装成纳米聚合物囊泡和靶向抗癌药物阿霉素的癌细胞线粒体。
Mitochondria are an attractive target to deliver anticancer drugs. We have synthesized a cationic triphenylphosphonium ion conjugated fluorescent polymer which self-assembles into nanosized polymersomes and targets the encapsulated anticancer drug doxorubicin to cancer cell mitochondria.