Cell Polarity: A Link to Epithelial-Mesenchymal Transition and Vascular Mimicry
Cell Polarity: A Link to Epithelial-Mesenchymal Transition and Vascular Mimicry
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DOI：
10.1615/critreveukaryotgeneexpr.2018020775
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发表时间：
2018-01-01
影响因子：
1.6
通讯作者：
Bhattacharya, Susinjan
中科院分区：
文献类型：
--
作者：
Bhattacharya, Susinjan
细胞极性是发育、细胞生理和组织稳态的基本过程。细胞极性丧失是癌症的一个特征。这篇综述强调了维持细胞极性的因素，并着眼于细胞极性，上皮间充质转化（EMT）和癌症之间的联系，最后试图绘制细胞极性和血管拟态EMT发生细胞之间的联系。
Cell polarity is an essential process for development, cell physiology and tissue homeostasis. Loss of cell polarity is a characteristic feature of cancer. This review highlights the factors involved in maintenance of cell polarity and looks at the link between cell polarity, epithelial mesenchymal transition (EMT) and cancer and finally tries to draw link between cell polarity and vascular mimicry in EMT occurring cells.