Phenomenon of "contact guidance" on the surface with nano-micro-groove-like pattern and cell physiological effects
Phenomenon of "contact guidance" on the surface with nano-micro-groove-like pattern and cell physiological effects
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纳米微沟纹表面“接触引导”现象及细胞生理效应
DOI：
10.1007/s11434-009-0366-1
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发表时间：
2009-09-01
影响因子：
--
通讯作者：
Chen Hong
中科院分区：
文献类型：
--
作者：
Zhou Feng;Yuan Lin;Chen Hong
材料表面形貌对细胞行为和生理功能有重要影响。在众多的图形中，类沟槽图形由于其所引起的“接触导引”现象而备受关注。本文主要综述了“接触导向”的形成及其对细胞行为和生理效应的影响。讨论了“接触制导”形成的可能机制。最后指出了今后的研究方向和潜在的应用前景。
The topography of material surface has important influence on cell behavior and physiological functions. Groove-like pattern has drawn much attention among various patterns, due to the phenomenon of "contact guidance" induced by this kind of topography. This review mainly focuses on "contact guidance" formation as well as its influence on cell behavior and physiological effects. The possible mechanisms of "contact guidance" formation were discussed. The research trend and the potential applications were also suggested.