FLS2:: An LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis
FLS2:: An LRR receptor-like kinase involved in the perception of the bacterial elicitor flagellin in Arabidopsis
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DOI：
10.1016/s1097-2765(00)80265-8
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发表时间：
2000-06-01
期刊：
影响因子：
16
通讯作者：
Boller, T
中科院分区：
文献类型：
--
作者：
Gómez-Gómez, L;Boller, T
鞭毛蛋白是细菌鞭毛的主要蛋白质，在拟南芥幼苗中增强防御反应并改变生长。以前，我们确定了FLS 1基因座，赋予鞭毛蛋白不敏感的Ws-0。为了鉴定参与鞭毛蛋白感知的其他组分，我们在鞭毛蛋白敏感的登录La-er中筛选鞭毛蛋白不敏感突变体。在这里，我们描述了一个新的基因座，FLS 2，通过地图为基础的战略的识别。FLS 2基因广泛表达并编码一种推定的受体激酶。FLS 2与已知的植物抗性基因以及与哺乳动物和昆虫的先天免疫系统相关的组分具有结构和功能同源性。
Flagellin, the main protein of the bacterial flagella, elicits defence responses and alters growth in Arabidopsis seedlings. Previously, we identified the FLS1 locus, which confers flagellin insensitivity in Ws-0. To identify additional components involved in flagellin perception, we screened for flagellin insensitivity mutants in the flagellin-sensitive accession La-er. Here, we describe the identification of a new locus, FLS2, by a map-based strategy. The FLS2 gene is ubiquitously expressed and encodes a putative receptor kinase. FLS2 shares structural and functional homologies with known plant resistance genes and with components involved in the innate immune system of mammals and insects.