STUDIES ON CYSTATHIONASE ACTIVITY IN RAT-LIVER AND BRAIN DURING DEVELOPMENT - EFFECTS OF HORMONES AND AMINO-ACIDS IN-VIVO
STUDIES ON CYSTATHIONASE ACTIVITY IN RAT-LIVER AND BRAIN DURING DEVELOPMENT - EFFECTS OF HORMONES AND AMINO-ACIDS IN-VIVO
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DOI：
10.1042/bj1361011
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发表时间：
1973-01-01
影响因子：
4.1
通讯作者：
HEINONEN, K
中科院分区：
文献类型：
--
作者：
HEINONEN, K
在发育过程中，大鼠肝脏中存在高活性的胱硫醚酶，但大鼠大脑中只有少量的活性。曲安西龙对胎儿肝脏胱硫醚酶活性没有影响，但在出生后大鼠中显着增加酶活性。l-甲状腺素显著降低新生大鼠肝脏胱硫醚酶活性;给予吡哆醛5′-磷酸盐不能阻止这种作用。左旋蛋氨酸显著增加新生大鼠肝脏胱硫醚酶活性。
High activity of cystathionase was present in rat liver but only low amounts of activity in rat brain during development. Triamcinolone had no effect on liver cystathionase activity in foetuses but increased the enzyme activity significantly in postnatal rats. l-Thyroxine decreased liver cystathionase activity significantly in newborn rats; administration of pyridoxal 5′-phosphate did not prevent this effect. l-Methionine significantly increased liver cystathionase activity in newborn rats.