Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity.
Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity.
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DOI:
10.1097/jes.0b013e31818782dd
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发表时间:
2008-10
影响因子:
5.7
通讯作者:
Fox DL
中科院分区:
文献类型:
--
作者:
Good DJ;Coyle CA;Fox DL
GOOD, DJ, CA COYLE, and DL FOX. Nhlh2: a basic helix-loop-helix transcription factor controlling physical activity. Exerc. Sport Sci. Rev., Vol. 36, No. 4, pp. 187Y192, 2008. In mice, targeted deletion of the basic helix-loop-helix transcription factor, nescient helix-loop-helix 2 (Nhlh2), leads to adult-onset obesity and reduced physical activity. We propose the novel hypothesis that transcriptional activity by Nhlh2 (NHLH2 in humans) controls either the ability or the motivation for exercise.