Ankle-arm index as a predictor of cardiovascular disease and mortality in the cardiovascular health study
Ankle-arm index as a predictor of cardiovascular disease and mortality in the cardiovascular health study
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DOI：
10.1161/01.atv.19.3.538
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发表时间：
1999-03-01
影响因子：
8.7
通讯作者：
Siscovick, D
中科院分区：
文献类型：
--
作者：
Newman, AB;Shemanski, L;Siscovick, D
通过踝臂指数（AAI）非侵入性测量的腿部外周动脉疾病（PAD）与临床表现的心血管疾病（CVD）及其危险因素相关。为了确定与低AAI相关的总死亡率、冠心病或卒中死亡率以及CVD事件与复发的风险，我们在5888名有或无CVD的老年人中研究了AAT与随后CVD事件的关系。在心血管健康研究的基线检查时，测量了5888名年龄大于或等于65岁的参与者的AAT。所有参与者都对普遍的CVD进行了详细的评估，并每6个月联系一次总死亡率和CVD事件（包括CVD死亡率，致命性和非致命性心肌梗死，充血性心力衰竭，心绞痛，中风和住院PAD）。6年时的粗死亡率在有CVD和低AAI的受试者中最高（32.3%）（P
Peripheral arterial disease (PAD) in the legs, measured noninvasively by the ankle-arm index (AAI) is associated with clinically manifest cardiovascular disease (CVD) and its risk factors. To determine risk of total mortality, coronary heart disease, or stroke mortality and incident versus recurrent CVD associated with a low AAI, we examined the relationship of the AAT to subsequent CVD events in 5888 older adults with and without CVD. The AAT was measured in 5888 participants greater than or equal to 65 years old at the baseline examination of the Cardiovascular Health Study. All participants had a detailed assessment of prevalent CVD and were contacted every 6 months for total mortality and CVD events (including CVD mortality, fatal and nonfatal myocardial infarction, congestive heart failure, angina, stroke, and hospitalized PAD). The crude mortality rate at 6 years was highest (32.3%) in those participants with prevalent CVD and a low AAI (P