Selective thoracolumbar/lumbar fusion for Syringomyelia-associated scoliosis: a case-control study with Lenke 5C adolescent idiopathic scoliosis.

Selective thoracolumbar/lumbar fusion for Syringomyelia-associated scoliosis: a case-control study with Lenke 5C adolescent idiopathic scoliosis.
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选择性胸腰椎/腰椎融合术治疗脊髓空洞症相关脊柱侧凸:Lenke 5C 青少年特发性脊柱侧凸的病例对照研究

DOI:
10.1186/s12891-020-03779-0
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发表时间:
2020-11-14
影响因子:
2.3
通讯作者:
Lao L
Lao L
中科院分区:
医学3区
文献类型:
--
作者:
Feng F;Shen H;Chen X;Liu Z;Chen J;Li Q;Lao L

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背景选择性胸腰椎融合技术被引入治疗青少年特发性脊柱侧凸(AIS)患者的胸腰椎/腰椎严重弯曲。从理论上讲,这种手术策略也适用于脊髓灰质炎患者。之前没有研究专门讨论选择性胸腰椎/腰椎融合术治疗脊髓灰质炎相关脊柱侧凸患者的有效性。本研究的目的是探讨选择性胸腰椎/腰椎融合术对脊髓灰质炎相关脊柱侧凸患者手术治疗的有效性。MethodsFrom 2010年2月至2016年9月,对14例脊髓灰质炎相关胸腰椎/腰椎弯曲患者进行回顾性分析。另外,30例Lenke 5C AIS患者作为对照组。两组均行后路选择性胸腰椎/腰椎融合术。对患者的人口统计学、手术、放射学和生活质量数据进行了随访。组内比较进行了每个parameter.ResultsThe两组匹配的年龄,性别,曲线特征,随访时间,以及所有术前影像学参数,除了胸椎后凸。术后胸腰/腰椎大弯平均矫正率脊髓空洞组为82.2 ± 7.8%,AIS组为82.5 ± 10.6%,P = 0.47,差异无统计学意义。两组未融合胸椎曲线改善相似(50.1 ± 16.5%vs.48.5 ± 26.9%,P = 0.29)。随访期间,脊柱侧凸矫正效果维持良好,未出现原有神经症状加重或新的永久性神经功能缺损。脊髓损伤组融合节段数明显多于AIS组(7.6 ± 1.4 vs.6.5 ± 1.2,P < 0.01)。平均随访47.6个月(36-81个月)。结论与AIS病例相似,选择性胸腰椎/腰椎融合术可有效、安全地矫正脊髓灰质炎相关性脊柱侧凸,手术效果满意。然而,与AIS组相比,脊髓灰质炎组平均需要额外的融合节段进行治疗(AIS组为7.6 vs 6.5)。
BackgroundSelective thoracolumbar/lumbar fusion technique was introduced to treat adolescent idiopathic scoliosis (AIS) patients with major thoracolumbar/lumbar curves. Theoretically, this surgical strategy could also be applied to syringomyelia patients. No previous study has specifically addressed the effectiveness of selective thoracolumbar/lumbar fusion for patients with syringomyelia-associated scoliosis. The aim of the study was to investigate the effectiveness of selective thoracolumbar/lumbar fusion for the surgical treatment of patients with syringomyelia-associated scoliosis.MethodsFrom February 2010 to September 2016, 14 syringomyelia-associated patients with major thoracolumbar/lumbar curves were retrospectively reviewed. Besides, 30 Lenke 5C AIS patients were enrolled as a control group. Posterior selective thoracolumbar/lumbar fusion was performed for both groups. Patients’ demographic, operative, radiological, and quality of life data were reviewed with follow-up. Intragroup comparisons were performed for each parameter.ResultsThe two groups were matched by age, gender, curve characteristics, duration of follow-up, and all preoperative radiographic parameters except for thoracic kyphosis. After surgery, the average correction rate of the major thoracolumbar/lumbar curve was 82.2 ± 7.8% in the syringomyelia group, which was not significantly different from that of AIS group (82.5 ± 10.6%,P= 0.47). A similar improvement of unfused thoracic curve was observed between the two groups (50.1 ± 16.5% vs. 48.5 ± 26.9%,P= 0.29). During the follow-up, the correction effect of scoliosis was well maintained, without aggravation of the original neural symptoms or fresh permanent neurological deficits. Of note, the number of fusion levels was significantly larger in syringomyelia group than that in AIS group (7.6 ± 1.4 vs. 6.5 ± 1.2,P< 0.01). The average follow up was 47.6 months (36–81 months).ConclusionSimilar to AIS cases, syringomyelia-associated scoliosis can be effectively and safely corrected by selective thoracolumbar/lumbar fusion with satisfactory surgical outcomes. However, the syringomyelia group, on average, required an additional fused segment for treatment as compared to the AIS group (7.6 versus 6.5 in the AIS group).
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