Hydronephrosis in inbred strains of mice with particular reference to the BRVR strain

Hydronephrosis in inbred strains of mice with particular reference to the BRVR strain
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近交系小鼠的肾积水,特别是 BRVR 系

DOI:
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发表时间:
1973
期刊:
Laboratory Animals. Journal of the Laboratory Animal Science Association
影响因子:
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通讯作者:
H. Fraser
H. Fraser
中科院分区:
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文献类型:
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作者:
D. Taylor;H. Fraser

文献摘要

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在同一群体饲养的13个近交系小鼠中,有6个发生了肾积水。其发病率仅在BRVR菌株中较高,其中约一半的病例只能在显微镜下检出。即使在严重异常的BRVR肾脏中也没有伴随感染,并且该疾病的发生率不受饮食变化的影响。在其他5个品系中发现的肾积水(不太常见)与BRVR小鼠的肾积水类型不同。
Hydronephrosis occurred in 6 of the 13 inbred mouse strains maintained in the same colony. Its incidence was high only in the BRVR strain, where about half of the cases could only be detected microscopically. There was no concomitant infection even in severely abnormal BRVR kidneys and the incidence of the condition was not influenced by dietary variation. The hydronephrosis found, less frequently, in 5 of the other strains was of a different type from that in BRVR mice.