EXTRACORPOREAL SHOCK-WAVE LITHOTRIPSY OF PANCREATIC CALCULI
EXTRACORPOREAL SHOCK-WAVE LITHOTRIPSY OF PANCREATIC CALCULI
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DOI：
10.1016/0016-5085(92)90110-k
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发表时间：
1992-02-01
期刊：
影响因子：
29.4
通讯作者：
CREMER, M
中科院分区：
文献类型：
--
作者：
DELHAYE, M;VANDERMEEREN, A;CREMER, M
采用体外冲击波碎石术(ESWL)治疗123例慢性重症胰腺炎患者主胰管结石。ESWL后的内窥镜治疗旨在恢复胰腺向十二指肠的血流。122例患者结石碎裂，111例主胰管直径缩小，72例主胰管完全清除。疼痛完全缓解(40/88)或部分缓解(35/88)与主胰管内窥镜引流的结果显著相关(例如，主胰管直径减小)。复发性疼痛最常与复发性胰管梗阻有关。ESWL前体重下降的76例患者中，54例体重增加。22例患者中有12例在治疗前和治疗后平均11个月进行了[14C]三油酸呼气试验，观察到外分泌功能的改善。主胰管梗阻解除后内分泌功能改善的发生率较低(4/41)。ESWL治疗重症慢性胰腺炎是一种新的、安全、高效的方法，可以方便、安全、高效地完成胰管梗阻的内窥镜手术。
Extracorporeal shock-wave lithotripsy (ESWL) has been used to disintegrate pancreatic stones located in the main pancreatic duct for 123 patients with severe chronic pancreatitis. Endoscopic management following ESWL is aimed at restoring the pancreatic flow to the duodenum. Stone disintegration was achieved in 122 patients, whereas a decrease in the main pancreatic duct diameter resulted in 111, and complete clearance of the main pancreatic duct was obtained in 72. Pain relief, complete (40/88) or partial (35/88), correlated significantly with the results of the endoscopic drainage of the main pancreatic duct (e.g., decrease in main pancreatic duct diameter). Relapsing pain was most often related to recurrent pancreatic duct obstruction. Of 76 patients whose body weight had decreased before ESWL, 54 gained weight. Improvement of the exocrine function, evaluated by the [14C]triolein breath test before and 11 months, on the average, after ESWL, was observed in 12 patients among 22 for whom this test was performed before and after treatment. Improvement of the endocrine function after relief of obstruction of the main pancreatic duct was less frequently recorded (4/41). ESWL of pancreatic stones is a new, safe, and highly effective method of facilitating the endoscopic procedures for relief of pancreatic duct obstruction in severe chronic pancreatitis.