Molecular Characterization of Pandemic H1N1 Influenza Viruses Isolated from Turkeys and Pathogenicity of a Human pH1N1 Isolate in Turkeys
Molecular Characterization of Pandemic H1N1 Influenza Viruses Isolated from Turkeys and Pathogenicity of a Human pH1N1 Isolate in Turkeys
复制标题
从火鸡中分离出的大流行 H1N1 流感病毒的分子特征以及人类 pH1N1 分离株在火鸡中的致病性
DOI:
10.1637/9558-942210-digest.1
复制
发表时间:
2010
影响因子:
3.1
通讯作者:
J. Pasick
中科院分区:
文献类型:
--
作者:
Y. Berhane;D. Ojkic;J. Neufeld;M. Leith;T. Hisanaga;H. Kehler;Á. Ferencz;H. Wojcinski;C. Cottam;M. Suderman;K. Handel;S. Alexandersen;J. Pasick
Important Findings Suspected human-to-animal transmission of the 2009 pandemic H1N1 (pH1N1) virus has been reported in several animal species, including pigs, dogs, cats, ferrets, and turkeys. This study describes the genetic characterization of pH1N1 viruses isolated from breeder turkeys that was associated with a progressive drop in egg production. The report provides additional evidence that pH1N1 can cross the species barrier and cause disease outbreaks in domestic turkeys. However, it appears that the reproductive status of the host as well as environmental factors such as concurrent infections, stress, the presence or absence of litter, and stocking density may also contribute to efficient infection and transmission of this agent.