AN ALTERNATIVE TO THE PROPORTIONATE MORTALITY RATIO
AN ALTERNATIVE TO THE PROPORTIONATE MORTALITY RATIO
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DOI：
10.1093/oxfordjournals.aje.a113161
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发表时间：
1981-01-01
影响因子：
5
通讯作者：
WANG, JD
中科院分区：
文献类型：
--
作者：
MIETTINEN, OS;WANG, JD
通常被认为证明使用比例死亡率比（PMR）比较接触和未接触人群是合理的条件，也允许计算关注的（死亡）原因与考虑的其他原因之间的死亡率比值（莫尔）。该莫尔将暴露者与非暴露者进行比较，等于将关注原因死亡与辅助（其他）原因死亡进行比较的暴露比值比，与PMR相反，可以将其解释为预期死亡率比或标准化死亡率比，假设是辅助原因死亡率与暴露无关。与此相关，莫尔不含PMR中的任意元素，这取决于随机原因域的大小。这些属性使得所提出的措施优于PMR统计上级。考虑PMR数据的拟议统计量还强调了将PMR研究视为病例参考研究的必要性，这对辅助原因（参考系列）的选择具有重要意义。
The conditions that are generally considered to justify the use of the proportionate mortality ratio (PMR) to compare exposed and nonexposed populations also permit the computation of the ratio of mortality odds (MOR) between the cause (of death) of interest and the other causes considered. This MOR comparing the exposed with the nonexposed equals the exposure odds ratio comparing deaths from the cause of interest with those from the auxiliary (other) causes, and, in contrast to the PMR, it can be interpreted as the observed-to-expected ratio or the standardized mortality ratio on the assumption that the mortality rate for the auxiliary causes is unrelated to the exposure. Related to this, the MOR is free of the arbitrary element in the PMR, which is dependent on the size of the auxiliary-causes domain. These properties make the proposed measure superior to the PMR statistic. Consideration of the proposed statistic for PMR data also underscores the need to view PMR studies as case-referent studies, and this has important implications for the choice of the auxiliary causes (reference series).