Animal models of tendon and ligament injuries for tissue engineering applications
Animal models of tendon and ligament injuries for tissue engineering applications
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DOI：
10.1016/s0142-9612(03)00507-6
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发表时间：
2004-04-01
期刊：
影响因子：
14
通讯作者：
Hankenson, KD
中科院分区：
文献类型：
--
作者：
Carpenter, JE;Hankenson, KD
动物模型仍然是对治疗肌腱和韧带损伤的新技术进行关键评估的重要组成部分。对这些模型进行适当的选择和分析是必要的。在评估潜在模型时应考虑的因素包括组织类型（韧带与肌腱、隐膜内与隐膜外）、要建模的损伤类型。测量治疗反应的技术，与先前发表的模型进行比较的便利性，以及最终转化为人体试验和最终临床应用的便利性。(C) 2003 Elsevier Ltd.版权所有。
Animal modeling continues to be an important component to the critical evaluation of new techniques to treat tendon and ligament injuries. Appropriate choice and analysis of these models is essential. Factors that should be considered in assessing a potential model include the tissue type (ligament versus tendon and intrasynovial versus extrasynovial), the type of injury to be modeled. the techniques of measuring the response to treatment, the ease of comparison to previously published models and finally, the ease of translation to human trials and eventually to clinical usage. (C) 2003 Elsevier Ltd. All rights reserved.