Dried blood spots: An evaluation of utility in the field
Dried blood spots: An evaluation of utility in the field
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DOI：
10.1016/j.jiph.2017.09.014
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发表时间：
2018-05-01
影响因子：
6.7
通讯作者：
Boulton, Matthew L.
中科院分区：
文献类型：
--
作者：
Su, Xu;Carlson, Bradley F.;Boulton, Matthew L.
背景：在资源匮乏的环境中进行的研究中，使用干血斑 (DBS) 比血清样本具有优势。本研究的目的是比较不同人口群体收集的足够点的数量。方法：从中国天津 3316 名 0-49 岁的个体中收集了 5 个 DBS，用于麻疹抗体研究；星展银行被评为“合格”或“不合格”。使用线性回归（以卡片上足够的 DBS 数量作为结果变量）来测试 DBS 充足性的预测因素。结果：23% 的参与者有 0 次足够的 DBS，24% 的参与者有 5 次足够的 DBS。婴儿充分 DBS 的平均次数为 1.68（
Background: Use of dried blood spots (DBS) offers advantages over serum samples in studies conducted in resource-poor settings. The aim of this study was to compare the number of adequate spots collected across different demographic groups.Methods: Five DBS were collected from 3316 individuals aged 0-49 years in Tianjin, China for a measles antibody study; DBS were rated "adequate" or "inadequate." Linear regression, with the number of adequate DBS on a card as the outcome variable, was used to test for predictors of DBS adequacy.Results: There were 0 adequate DBS for 23% of participants and 5 adequate DBS for 24%. Mean number of adequate DBS was 1.68 in infants (